GFI BACKUP home edition is my first PC backup recommendation for the average user. GFI Backup replaces the old Titan Backup.
It is fairly easy to use, backs up archives as zip files with or without encryption, has an easy to use scheduler, supports a variety of backup locations, will do incremental and differential backups, and has a restore function that will help you restore complete archives or individual files. GFI also has support for backing up files even if they are in use. All in all if you have already been using Titan Backup in the past you will find GFI to have a similar user experience with some nice extra features. http://www.gfi.com/backup-hm